David - Bioinfo

I found 10,000 variants. The lab expected 5. Did I mis-call indels? Is there a batch effect? Did someone accidentally use the mouse reference genome again? (It happened once. Once.)

Hi! I’m David. Ask me what I do, and you’ll get a different answer depending on the day. david bioinfo

Why ‘rm -rf’ is scarier than a pipette tip, and other truths of digital biology. Introduction: Hello, World (of Omics) I found 10,000 variants

You can have the cleanest pipeline, the most parallelized code, and a server with 1TB of RAM. But if you don’t understand the biological question, you’re just moving bytes around. Is there a batch effect

Here’s a structured blog post tailored for someone named working in bioinformatics . It’s written to be engaging, professional, and relatable to peers in computational biology. Title: From Command Lines to Chromosomes: A Day in the Life of David, Bioinformatician